Michael M. Morgan
Ph.D. University of California, Los Angeles, 1989
Office: CLS 208G (Vancouver Campus)
Phone: (360) 546-9726
- Psychology 372: Biological Basis of Behavior
- Psychology 401: Historical Development of Psychology
- Psychology 504: History of Psychology: Theoretical and Scientific Foundations
- Psychology 574: Clinical and Experimental Biopsychology
- Neuroscience 302: Foundations of Neuroscience
- Neural Mechanisms of Pain Modulation
- Animal models of opioid withdrawal
Pain is the most costly medical problem in the United States. Pain treatments are limited by poor analgesic efficacy or severe side effects (e.g., opioid dependence). My lab uses behavioral pharmacological approaches to address this problem in three ways: First, we are developing new ways to assess pain in animals such as measuring depression of activity (e.g., decreases in wheel running) to more closely mimic the effects of pain in people. Second, we are studying how the midbrain periaqueductal gray contributes to opioid analgesia and tolerance. Third, we are developing novel methods to assess spontaneous opioid withdrawal in rats in order to create a better model of opioid withdrawal in humans. Our primary goal is to lay the groundwork for the development of more effective treatments for pain and opioid withdrawal.
Morgan, M. M., Peecher, D. L, & Streicher, J. M. (2021). Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat. Behavioural Brain Research, 397:112953. PMID: 33031872
Stickney, J. S. & Morgan, M. M. (2021). Social housing promotes recovery of wheel running depressed by inflammatory pain and morphine withdrawal in male rats. Behavioural Brain Research, 396:112912. PMID: 32949642
Morgan, M. M., Tran, A., Wescom, R. L., & Bobeck, E. N. (2020). Differences in Antinociceptive signaling mechanisms following morphine and fentanyl microinjections into the rat periaqueductal gray. European J. Pain, 24(3):617-624. PMID 31785128.
Bobeck, E.N., Schoo, S.M., Ingram, S.L., Morgan, M.M. (2019). Lack of antinociceptive cross- tolerance with co-administration of morphine and fentanyl into the periaqueductal gray of male Sprague-Dawley rats. J Pain, 20(9): 1040-1047. PMID: 30853505.